Table 2.

Brain Aβ40 and Aβ42 in TBS and formic acid extracts after intracerebroventricular infusion of GM1 or vehicle

	n	Aβ40      Aβ42
		Picomoles of Aβ per gram of tissue
TBS-soluble Aβ
Vehicle infusion	7	1.1  ± 0.1	0.7  ± 0.1
GM1 infusion	4	5.8  ± 1.6	2.1  ± 0.2
		(p  = 0.04)	(p  = 0.001)
FA-soluble Aβ
Vehicle infusion	7	179  ± 43	210  ± 37
GM1 infusion	4	212  ± 26	231  ± 15
		(p  = 0.29)	(p  = 0.98)

Aβ was extracted by the four-step method (Kawarabayashi et al., 2001). Data are presented as mean ± SEM.