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PTX treatment and ICI 118,551 remove the inhibitory action of ISO. A, The PTX-treated cell was first superfused with control external solution and then exposed to 1 μm ISO for the period indicated. B, The cell was first superfused with control external solution and then exposed to the β2-AR-selective antagonist ICI 118,551 (0.1 μm) and ISO (1 μm) for the periods indicated. Symbols, lettering, andtraces have the same meaning as in previous figures.
