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. 2003 May 1;23(9):3649–3657. doi: 10.1523/JNEUROSCI.23-09-03649.2003

Fig. 3.

Fig. 3.

Comparison of the magnitude and washout of the clonazepam-mediated suppression of spikes during evoked oscillations in slices from rats, wild-type (WT) mice, α1(H101R) mice, and α3(H126R) mice. For each case, the total number of spikes in each evoked oscillation, relative to control, is plotted for various conditions (control, CZP application, and at 5 min intervals during drug washout). For rat slices, data from recordings in the ventrobasal complex (VB, ○) and the thalamic reticular nucleus (TRN, ▪) are plotted separately. In mouse slices, all recordings were made in VB. CZP significantly reduces the number of spikes during evoked oscillations in rat TRN, rat VB, WT mice, and α1 mutant mice but has no effect in α3 mutant mice (*p < 0.05; ***p < 0.001). Error bars indicate ± 1 SEM.