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. 2019 Sep 12;14(9):e0221899. doi: 10.1371/journal.pone.0221899

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© 2019 Liu et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — Lung slices were prepared from GSTCD^+/+ and GSTCD^-/- mice. (A) And (B) comparison of time courses of averaged contraction of slices in GSTCD^+/+ following either PBS or LPS treatment. (C) And (D) comparison of time courses of averaged contraction of slices in GSTCD^-/- following either PBS or LPS treatment. (E) Representative airway in GSTCD^+/+ (upper row) and GSTCD^-/- (lower row) stimulated by Mch (1 μM) before and after LPS treatment. Images of airways were taken following a 5-minute incubation of drugs and control (in absence of Mch). (F) Comparison of % decrease of contractility of airways before and after LPS treatment in GSTCD^+/+ and GSTCD^-/- groups. * Compared between LPS in GSTCD^+/+ PCLS and GSTCD^-/- PCLS P <0.05.