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. 2019 Sep 12;14(9):e0222436. doi: 10.1371/journal.pone.0222436

Table 3. Stem MAb neutralization against A/Puerto Rico/8/1934 escape mutants.

HA-pseudovirus neutralization titer (μg/ml) Plaque reduction titer (μg/ml)
Mutants 4C2 (IgG1) C179 CR6261 FI6 4C2 (IgG1) C179 FI6
WT 0.6 0.31 0.09 0.11 12.8 27.7 3.7
K55E 3.42 2.02 0.43 0.53 35.2 25.7 2.4
V444L 3.01 1.73 0.38 0.49 29.2 68.8 7.1
K55E.V444L 4.53 2.81 0.42 0.54 63.2 91.2 5.9