. 2003 Feb 15;23(4):1506–1516. doi: 10.1523/JNEUROSCI.23-04-01506.2003

Table 1.

Parameters in computer simulation

Description	Symbol	Value	Range
Maximal Na⁺conductance	G_Na	100 nS	50 to 130 nS
Membrane capacitance	C_m	15 pF	10 to 20 pF
Leak conductance	G_leak	0.5 nS	0.2 to 0.9 nS
Leak reversal potential	E_leak	−56 mV	−60 to −55 mV
Duration of action potential	T_AP	1.5 msec	1.3 to 2.5 msec
Fractional decrease ins₂ after spike	s $_{2}^{factor}$	0.23	0.13 to 0.34
Variance ofI_noise	ς_noise	4 pA²	3 to 8 pA²
Equilibrium potential for Na⁺	E_Na	35 mV	N/A
Trigger voltage for voltage-clamp switch	θ	−15 mV	N/A

G_Na was determined from the maximum amplitude of the Na⁺ current. C_m was the average measured capacitance. G_leak was measured from the conductance during white noise current injection of 16 pA² variance. T_AP was the average time between the spike waveform exceeding the voltage θ and returning to rest. I_noise was determined from the current fluctuations during voltage clamp at −60 mV.