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. 2003 Apr 15;23(8):3538–3546. doi: 10.1523/JNEUROSCI.23-08-03538.2003

Fig. 3.

Fig. 3.

Synaptic inhibition can suppress pacemaker bursting. A, Population bursts (∫PBC) and some pacemakers cease bursting when 8 mm[K+]o aCSF is exchanged with 3 mm [K+]o aCSF (arrow indicates onset of exchange). B, Expanded record of neuron bursting in 8 mm[K+]o aCSF. C, Relatively tonic spiking in 3 mm[K+]o aCSF. D, The neuron continues to spike tonically in 3 mm[K+]o aCSF after blockade of glutamatergic transmission with CNQX and CPP. E, Endogenous bursting is restored after subsequent blockade of synaptic inhibition with strychnine and bicuculline. y-Axis scale in B applies to A–E.x-Axis scale in B applies toC–E.