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. 2019 Sep 12;14(9):e0222408. doi: 10.1371/journal.pone.0222408

Table 1. Characteristic of the included studies.

First author, Year Country Disease No. of patients (Exp/control) No. of catheters (Exp/control) Tunneled or nontunneled catheter No. of catheters days (Exp/control) Intervention
Exp Control
Sanders 2008[16] New Zealand hematology 34/30 34/30 tunneled 5000/3537 70% ethanol heparin
Slobbe 2010[17] Netherlands hematology 376 226/222 tunneled 14262/13483 70% ethanol 0.9% NaCl
Broom 2012[18] Australia hemodialysis 25/24 25/24 tunneled 3614/1834 70% ethanol heparin
Yang 2013[19] China hemodialysis 20/20 20/20 not reported not reported 70% ethanol heparin
Sun 2014[20] China hemodialysis 16/16 16/16 tunneled 4449/4363 70% ethanol heparin
Worth 2014[21] Australia hematology 42/43 42/43 tunneled 2216/2657 70% ethanol heparin
Schoot 2015[22] Netherlands pediatric oncology 153/154 153/154 tunneled 20916/19915 70% ethanol heparin
Souweine 2015[23] France renal-replacement therapy or plasma exchange 730/730 1106/1066 nontunneled 6541/6496 60% wt/wt ethanol 0.9% NaCl
Salonen 2017[24] USA parenteral nutrition 18/20 18/20 not reported 2597/ 3125 70% ethanol heparin

Exp, experimental group; Control, control group