Table 3. Methodological quality of the included studies.

First Author, Year	Random sequence generation	Allocation concealment	Blinding of participants and personnel	Blinding of outcome assessment	Incomplete outcome data	Selective reporting	Other source of bias
Sanders 2008[16]	Computer-generated	Pharmacy	Low risk	High risk	Low risk	Low risk	Unclear
Slobbe 2010[17]	Computer-generated	Pharmacy	Low risk	Low risk	Low risk	Low risk	Unclear
Broom 2012[18]	Computer-generated	Central distribution	High risk	High risk	Low risk	Low risk	Unclear
Yang 2013[19]	Unclear	Unclear	High risk	High risk	Low risk	Unclear	Unclear
Sun 2014[20]	Computer-generated	Unclear	High risk	High risk	Low risk	Low risk	Unclear
Worth 2014[21]	Unclear	Unclear	High risk	High risk	Low risk	Unclear	Unclear
Schoot 2015[22]	Computer-generated	Central distribution	Low risk	Low risk	Low risk	Low risk	Unclear
Souweine 2015[23]	Unclear	Unclear	Low risk	High risk	Low risk	Low risk	Unclear
Salonen 2017[24]	Computer-generated	Unclear	Low risk	Low risk	Low risk	Low risk	Unclear