Table 4. Adverse events reported in the included trials.
| First Author, Year | Adverse events | |
|---|---|---|
| Exp | Control | |
| Sanders 2008[16] | Dyspnea immediately after the first treatment (n = 1) | Unusual taste sensation and anxiety (n = 1) |
| Slobbe 2010[17] | Facial flushing (n = 39); nausea/vomiting (n = 20); altered taste (n = 31); dizziness/drowsiness (n = 41); syncope shortly after the first treatment (n = 1) | Facial flushing (n = 17); nausea/vomiting (n = 17); altered taste (n = 19); dizziness/drowsiness (n = 10) |
| Broom 2012[18] | Stinging at the catheter exit site (n = 1); dry lips and thirst (n = 1) | Bleeding (n = 1) |
| Yang 2013[19] | Dizziness/drowsiness (n = 1) | No adverse events |
| Sun 2014[20] | Facial flushing (n = 1); bleeding after insertion (n = 1); bad smell (n = 1) | Bleeding (n = 4) |
| Worth 2014[21] | Chest discomfort (3); nausea (n = 1) | No adverse events |
| Schoot 2015[22] | Nausea (n = 28); vomiting (n = 12); altered taste (n = 89); dizziness (n = 19); flushing (n = 31); drowsiness (n = 8); pain with injection (n = 8) | Nausea (n = 14); vomiting (n = 9); altered taste (n = 26); dizziness (n = 4); flushing (n = 4); drowsiness (n = 3); pain with injection (n = 4) |
| Souweine 2015[23] | No adverse events | No adverse events |
| Salonen 2017[24] | No adverse events | No adverse events |
Exp, experimental group; Control, control group