Table 2.
Scoresa |
|||||||||
---|---|---|---|---|---|---|---|---|---|
Total AUC During RT | |||||||||
Baseline (Cycle 0) |
(All Cycles) |
Post RT at 3 mo |
|||||||
Characteristics | Placebo | NAC | P Valueb | Placebo | NAC | P Valueb,c | Placebo | NAC | P Valueb |
Sticky saliva | |||||||||
Daytime | 11.1 | 6.5 | .38 | 45.2 | 26.1 | .04 | 50.0 | 35.2 | .40 |
Nighttime | 8.9 | 5.6 | .87 | 34.5 | 29.1 | .56 | 55.6 | 22.2 | .24 |
Total | 10.2 | 6.1 | .55 | 40.9 | 27.2 | .12 | 51.9 | 30.9 | .29 |
Xerostomia | |||||||||
Daytime | 15.9 | 13.9 | .58 | 44.1 | 27.3 | .02 | 46.3 | 29.6 | .59 |
Nighttime | 29.6 | 20.4 | .44 | 39.8 | 31.3 | .22 | 36.1 | 27.8 | .76 |
Total | 20.5 | 16.0 | .40 | 43.8 | 28.5 | .02 | 42.2 | 28.9 | .65 |
Abbreviations: AUC = area under the curve; NAC = N-acetylcysteine; RT = radiotherapy.
Lower scores indicate better quality of life.
Calculated with equal variance t testing.
Bold indicates statistical significance.