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. Author manuscript; available in PMC: 2019 Sep 12.
Published in final edited form as: Med Image Anal. 2014 Jul 5;18(7):1132–1142. doi: 10.1016/j.media.2014.06.008

Fig. 4.

Fig. 4

The various inputs to POSSUM to simulate the MRI phase images. Lesions are manually drawn in the input phantom image. The B0 inhomogeneity file describes change in magnetic field strength inside the cranium due to tissue susceptibility differences. To calculate these distortions, Maxwell’s equations are solved at each voxel in an air-tissue segmentation volume using the perturbation method. Finally, the MRI pulse sequence (eg. EPI) characteristics can be specified for each simulation.