Table 2:
Biomarker | Statin user | Non-user | P-value |
---|---|---|---|
ACR, mg/g | 7.4 (3.8, 18.5) | 6.0 (3.5, 15.6) | <0.01 |
ACR > 30, mg/g | 19% | 18% | 0.62 |
α1m, mg/dL | 1.3 (0.7, 3.0) | 1.5 (0.7, 3.3) | 0.90 |
Detectable α1m | 82% | 84% | 0.56 |
IL-18, pg/mL | 32 (16, 58) | 38 (17, 66) | 0.25 |
KIM-1, pg/mL | 604 (301, 1095) | 645 (347, 1164) | 0.17 |
PIIINP, ng/mL | 6.6 (3.5, 12.0) | 6.8 (3.9, 13.7) | 0.95 |
eGFR, ml/min/1.73m2 | 90 (72, 101) | 91 (77, 103) | 0.14 |
Data are presented as Median (IQR) or numbers (percent).
Abbreviations: ACR, albumin-to-creatinine ratio; α1m, α-1-microglobulin; eGFR, estimated glomerular filtration rate; IL-18, interleukin 18; KIM-1, kidney injury molecule-1; PIIINP = pro-collagen type III N-terminal pro-peptide.
Estimates shown after applying inverse probability of treatment weights.