Cumulative distribution (% of total) of asymmetric synapses onto spines by length in nucleus accumbens shell for each of the groups up to 1.00 µm (A), and for a focused comparison of the saline and nicotine sedentary groups (B), the nicotine sedentary and exercise groups (C), and the saline sedentary and nicotine exercise groups up to to 0.40 µm. Asterisks indicate significant differences at a p < 0.05 (*) or 0.01 level (**). Exer, exercise; Nic, nicotine; Sal, saline; Sed, sedentary.