Figure 6. Hippocampal atrophy at P40 resulting from neonatal HI at P10 does not correlate with Calb1 deficits.

Box and whiskers plot (A) represent the residual hippocampal volumes in mm³ for of sham, normothermia (NT), and therapeutic hypothermia (TH). Boxes are limited by the 75^th and 25^th percentiles (interquartile range, IQR) and whiskers are limited by the last data point within 1.5 times the IQR from the median (continuous line inside the box). Analysis by Kruskal-Wallis ANOVA with Dunn-Bonferroni correction; *, adjusted p-value <0.05. Calb1 expression in the whole hippocampus were correlated with residual hippocampal volumes in males and female mice (B). Spearman correlations were applied. Continuous line represents the predicted linear regression and discontinuous lines represent the projection to the 95% confidence interval. p-value < 0.05 were considered significant.