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. 2019 Sep 6;10:2116. doi: 10.3389/fimmu.2019.02116

Figure 1.

Figure 1

Germinal center reaction kinetics with varying antibody feedback strength. The scaling factor N is proportional to the strength of the antibody feedback onto the simulated GC. (A) Fraction of FDC antigen bound in immune complexes. (B) Concentration of free antigen. (C) GC volume kinetics measured as number of GC-BCs. (D) Total number of plasma cells generated in the simulated GC reaction over time.