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. 2019 Sep 6;10:2116. doi: 10.3389/fimmu.2019.02116

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Copyright © 2019 Arulraj, Binder, Robert and Meyer-Hermann.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Initialization of a GC (N = 1) with varying delay with respect to early GCs simulated with different scaling factors N. Mean affinity of plasma cells on day 5 (A) and day 21 (B) after GC initialization. Immune power (IP) (defined in Equation 4) of the delayed GC on day 5 (C) and day 21 (D).