FIGURE 4.

Analyses of AmnE hexameric interface. (A) Details of six His¹²³ located on the Lp3 are shown using sticks. (B) Hydrophobic loop Lp3 in trimeric structures of AmnE, the hydrophobic residues (Val¹²², Leu¹²⁵, and Leu¹³⁰) are shown in orange sticks. The three residues of Arg⁵⁶ that participate in hydrogen-bond formations in the hexameric structure are shown in green sticks. (C) Details of hydrogen bonds connecting Arg⁵⁶ with Met⁹⁶ and Pro¹²⁶ are shown using sticks. (D) Hydrophobic loop Lp3 in the trimeric structures of AmnE and the hydrophobic residues (Val¹²², Leu¹²⁵, and Leu¹³⁰) are shown in orange sticks. The residues of Met⁹⁶ and Pro¹²⁶ that participate in hydrogen bond formations in the hexameric structure are shown in white sticks. The figure was produced with PyMOL (http://www.pymol.org).