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. 2019 Sep 6;10:2074. doi: 10.3389/fmicb.2019.02074

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Copyright © 2019 Lee, Lee, Jeong, Hwang, Kim, Cho, Palsson and Cho.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genome-wide determination of transcription units (TUs). (A) Example of each TU category. (B) The number of TUs determined from transcription start site (TSS) and transcript 3′-end position (TEP) information. (C) Characterization of non-coding TUs. sRNA and cis-regulatory TUs were searched against Rfam database. (D) The functional relatedness of genes in a same poly-cistronic TU. The functional enrichment was determined as the maximum frequency of genes with same COG functional category in a single poly-cistronic TU. (E) The number of TU clusters separated by the number of comprised genes. (F) Proportional relationship between the number of TUs in a TU cluster and the number of genes in the TU cluster. (G) The RNA-Seq profile of TU cluster for ectoine biosynthesis genes.