Table 4.
Structures of MISN and structure of switch nucleic acid molecules.
| miRNA | Structure | Sequence number |
|---|---|---|
| mmu miR-34a | 5′-QD565-TCG CTGT ACAACCAGCTAAGACACTGCCA GTCGCTTT-3′ | 1 |
| mmu mir-106b | 5′-QD565-TCG CTGT ATTTCACGACTGTCACGTCTA GTCGC TTT-3′ | 2 |
| mmu miR-124b | 5′-QD565-TCG CTGT GGCATTCACCGCGTGCCTTA GTCGCTTT-3′ | 3 |
| mmu miR-146b | 5′-QD565-TCG CTGT AGCCTATGGAATTCAGTTCTCA GTCGCTTT-3′ | 4 |
| mmu mir-153 | 5′-QD565-TCG CTGT AACGTATCAGTGTTTTCACTAG GTCGC TTT-3′ | 5 |
| mmu mir-155 | 5′-QD565-TCG CTGT AATTACGATTAACACTATCCCCA GTCGC TTT-3′ | 6 |
| mmu miR-181a | 5′-QD565-TCG CTGT ACTCACCGACAGCGTTGAATGTT GTCGCTTT-3′ | 7 |
| mmu miR-200a | 5′-QD565-TCGCTGT ACATCGTTACCAGACAGTGTTA GTCGCTTT-3′ | 8 |
| hsa miR-34a | 5′-QD565-TCGCTGT ACAACCAGCTAAGACACTGCCA GTCGCTTT-3′ | 9 |
| hsa mir-106b | 5′-QD565-TCGCTGT ATTTCACGACTGTCACGTCTA GTCGC TTT-3′ | 10 |
| has miR-124b | 5′-QD565-TCGCTGT GGCATTCACCGCGTGCCTTA GTCGCTTT-3′ | 11 |
| hsa miR-146b | 5′-QD565-TCGCTGT AGCCTATGGAATTCAGTTCTCA GTCGCTTT-3′ | 12 |
| has mir-153 | 5′-QD565-TCGCTGT AACGTATCAGTGTTTTCACTAG GTCGC TTT-3′ | 13 |
| hsa mir-155 | 5′-QD565-TCGCTGT AATTACGATTAGCACTATCCCCA GTCGC TTT-3′ | 14 |
| hsa miR-181a | 5′-QD565-TCGCTGT ACTCACCGACAGCGTTGAATGTT GTCGCTTT-3′ | 15 |
| hsa miR-200a | 5′-QD565-TCGCTGT ACATCGTTACCAGACAGTGTTA GTCGCTTT-3′ | 16 |
| Switch nucleic acid molecule | 5′-biotin-AGCGA-BHQ2–3′ |
(The underlines mean target sequence).