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. 2019 Aug 9;18:45–55. doi: 10.1016/j.omtn.2019.07.022

Figure 1.

Figure 1

Flow Chart of SKF-LDA Applied to lncRNA-Disease Association Prediction

(A–D) SKF-LDA consists of four steps: (A) constructing the lncRNA-disease correlation matrix; (B) calculating the two similarities of lncRNA and disease similarity, respectively; (C) using SKF integration similarity; and (D) obtaining the prediction matrix by Laplacian regularized least squares.