Table 3.

Comparison of test outcomes from MP (High/Low Risk) between NGS assessed at Agendia Amsterdam central laboratory and NGS assessed at the beta sites (n = 114^∗). These results show a Negative Predictive Agreement (Low Risk) of 98.3% (58/59, 95% CI: 91.0–99.7), a Positive Predictive Agreement (High Risk) of 89.1% (49/55, 95% CI: 78.2–94.9), a concordance of 93.9% and a Cohen's kappa of 0.88.

		NGS Agendia
		High Risk	Low Risk	Total
NGS Beta Sites	High Risk	49	1	50
	Low Risk	6	58	64
	Total	55	59	114∗

^∗For 10 samples, no NGS results were obtained at Agendia.