Table 1.

Association of Pollen miRNA Expression and Respiratory Diseases

	Offspring 8 (n=2776)
	Prevalence of exRNA Expression					exRNA Cq Expression Values
	Positive Diagnosis		Negative Diagnosis		p Value	Positive Diagnosis		Negative Diagnosis		p Value
	N	%	N	%		Mean	SD	Mean	SD
COPD
pde-miR946	0	0	52	2	0.27	–	–	52	0.02	–
pta-miR1310	4	7	199	7	0.79	4	0.07	199	0.07	0.48
pta-miR948	9	15	528	20	0.32	9	0.15	528	0.20	0.92
ASTHMA
pde-miR946	2	1	50	2	0.22	2	0.01	50	0.02	0.57
pta-miR1310	18	8	189	8	0.92	18	0.08	189	0.08	0.67
Pta-miR948	50	22	487	20	0.46	50	0.22	487	0.20	0.29
HAY FEVER
pde-miR946	10	1	43	2	0.09	10	0.01	43	0.02	0.32
pta-miR1310	55	7	152	8	0.38	55	0.07	152	0.08	0.79
pta-miR948	177	22	361	19	0.04	177	0.22	361	0.19	0.99

Expression of pine pollen miRNAs in 2,782 people of Offspring 8 was as follows: pde-miR946 was present in 2% (n = 53), with Cq = 20.7 ± 3; pta-miR1310 was present in 8% (n = 208), with Cq = 8.3 ± 3; pta-miR948 was present in 20% (n = 543), with Cq = 20.8 ± 1.

There was no association with sex in this study.