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CBD treatment significantly increases the expression of cytokeratin 17 and 16 in mouse epidermis. (A) Representative images of cytokeratin 17 and 16 immunohistochemistry from mouse skin after 5 days of treatment with vehicle, CBD 0.1% or 1% (B) Quantification of cytokeratin 17 and 16 stained areas in mouse epidermis. *P < 0.05, ***<0.001 compared with control. Scale: 200 (left) and 100 μm (right). n = 14 for vehicle treated samples and n = 10 for CBD treated samples.
