Table 2.

Grade 3 or 4 adverse events

Toxicity	Pazopanib without ASM (n = 49) n (%)	Pazopanib with ASM (n = 42) n (%)	P value
Blood pressure	18 (37)	8 (19)	0.069
Blood bilirubin	0	0	NA
Alanine aminotransferase	5 (10)	3 (7)	0.72
Aspartate aminotransferase	5 (10)	2 (5)	0.44
Fatigue	1 (2)	2 (5)	0.59
Nausea	0	1 (2)	0.46
Anorexia	2 (4)	1 (2)	1.0
Diarrhea	0	1 (2)	0.46
Any grade 3 or 4 toxicity	22 (45)	13 (31)	0.20

ASM, acid‐suppressive medication.