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(A) Global years of life lost due to diseases in 2017. (B) The top 18 antimicrobial drug–resistant threats compiled by the U.S. Centers for Disease Control and Prevention (CDC). Extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae. (C) Annual global mortality projected for 2050. Adapted from the Global Burden of Disease Study (1), U.S. CDC (5) and O’Neill (6).
