Fig. 2.

Kaplan-Meier curves for OS. a OS curves for the favorable and unfavorable subsets of patients with CUP in the full-analysis set. b OS curves for the unfavorable subset of CUP patients in the full-analysis set according to the prognostic metastatic (meta) pattern in which lesions are limited to multiple LNs. c, d OS curves for CUP patients in the biomarker-analysis set according either to the TPS for PD-L1 (c) or to CD8⁺ TIL density (d). One patient with only one cell block specimen available was excluded from the analysis of CD8⁺ TIL density because of the absence of tissue on the slide. Vertical lines on the curves denote censoring. NR, not reached