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. 2019 Sep 13;38:404. doi: 10.1186/s13046-019-1411-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — SCP2 and hypercholesterolemia regulated PA cell growth in vivo. a Schematic of dietary challenge and medication administration in mice injected with either Vector or SCP2-OE GH3 cells. HCD stands for high cholesterol diet. b Excised tumors in different groups are shown. c Growth curve showing the changes in the tumor volume in mice after different treatments. d Weight of the excised tumors in each group. e Plasma cholesterol level in mice in each group after sacrifice. f Protein expression level of GLI1 in excised tumors were examined by Western blotting. An unpaired t-test was used to assess statistical significance. **P < 0.01; ***P < 0.001; #, not significant.