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. 2019 Aug 30;21(8):e12785. doi: 10.2196/12785

Table 3.

Summary of 6 studies that included data from dedicated or purposive ICTa-monitoring solutions, such as phone-based automated interviews, Nintendo Wii, and virtual reality (Group 3).

First author (year), country Technology description Study description: design; number and type of subjects (number living aloneb, if relevant) and setting; duration Cognitive status and number of participants; age; number of male and/or female participants Main results
Mundt (2007), United States [33] Use of IVRc technology (ie, pressing keys) to administer simple cognitive evaluations by phone during a 20-minute, computer-automated telephone call Observational comparative study; 107 community-dwelling participants; 24 weeks: IVR administered at home at weeks 4, 12, and 20 36 cognitively normal, (MMSEd=28.1), 37 MCIe (MMSE=25.6), 34 mild dementia (MMSE=20.0); mean age 76.7 years; 42% female The automated administration of IVR simple cognitive tests via phone calls reliably and validly discriminated cognitive functioning among normal, MCI, and mild dementia.
Allard (2014), France [34] Monitoring of behavior, semantic memory performance, and daily life experiences using a personal digital assistant five times a day Observational study; 60 older adults; 7 days 60 healthy participants (mean MMSE=27.0); mean age 75.1 years; 45% female Magnetic resonance imagery markers were significantly associated with mobile assessments of semantic memory performance.
Brown (2016), United Kingdom [35] Touch screen system to assess multiple domains of health and behavior; cognitive tasks scheduled once per day Observational study; 40 community-dwelling adults; three periods of approximately 7 days 40 healthy participants (mean MMSE=28.63); mean age 72 years; 24 females, 16 males Convergent validity with, and similar levels of, reliability to the standard cognitive battery.
Seelye (2016), United States [36] Completion of a short 12-item weekly online questionnaire of health and life events, administered on desktop computers Observational study; 83 independent, community-dwelling older adults; 1 year 59 healthy (MMSE=28.8), 24 MCI (MMSE=27.4); mean age 86.2 and 87.9 years, respectively; 88% and 75% female, respectively Online questionnaire performance significantly correlated to cognitive test. MCI participants submitted their questionnaires progressively later in the day and they needed greater assistance from staff as compared with intact participants.
Zygouris (2017), Greece [37] Tablet personal computer with software enabling the self-administration of a cognitive assessment through virtual reality Comparative, two-arm, observational study; 12 elderly living at home; 1-month follow-up 6 healthy and 6 MCI; mean 64 years; 3 males, 9 females Performances to complete the given exercise differed significantly between healthy and MCI groups, yielding a correct classification rate of 92% for MCI detection.
Leach (2018), United States [38] A Nintendo Wii balance board used to quantify postural sway twice daily, under a single-task condition and under a dual-task condition, using a daily word-search task administered via a Nook tablet Observational study; 20 healthy community-dwelling elderly; 30 days Mean MMSE=28.6; mean age 87.0 years; 65% females Linear relationships were observed between the day-to-day variability in postural sway and cognitive status.

aICT: information and communication technologies.

bThe number of participants living alone is specified when the information is relevant; for example, for ambient sensors but not for wearables devices.

cIVR: interactive voice response.

dMMSE: Mini Mental State Examination.

eMCI: mild cognitive impairment.