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ER stress and autophagy are related in HCC specimens, and patients with both PERK and Beclin1 expression have a shorter overall survival time. (A-D) Expression of PERK, IRE1, ATF6, and Beclin1 in HCC specimens (streptavidin-peroxidase ×200). (E) Comparison of Kaplan-Meier cancer-specific survival curves between the matched PERK- and Beclin1-positive and PERK- and Beclin1-negative groups.
