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. 2019 Sep 6;10:2119. doi: 10.3389/fimmu.2019.02119

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Copyright © 2019 Teige, Kumar, Johansen, Wessel, Vendramin, Lund, Rimstad, Boysen and Dahle.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Detection of cross-binding antibodies induced by PRV3 infection in rainbow trout. (A) Field samples from a PRV-3 outbreak in rainbow trout analyzed with LM-PRVσ1, μNS, and μ1c (PRV-1) coupled beads in the immunoassay. Significant difference between MFI of LM-PRVσ1 beads and the other beads are indicated by asterisks (Mann-Whitney test). (B) MFI from blood and plasma samples from individuals experimentally infected with PRV and uninfected controls using LM-PRVσ1 and LM-WSSV-ICP11 coupled beads. All samples were heat-treated.