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. 2019 Sep 10;7:e7456. doi: 10.7717/peerj.7456

Table 2. Function enrichment analysis for the genes in ceRNA network.

Category Term P-value Genes
Biology process GO:0006793 ∼ phosphorus metabolic process 0.00122 STK38, SLC20A1, ERBB3, NUAK1, MKNK1, ABI1, PIP5K1A, TRIB1, MAP3K3, SRPK2, MINPP1, ADAM10, STK24, MSH2, PRKCI, PKN2, PTPN12, GAK, MAP4K4, MTMR11, MAPK6, GSK3B, DYRK1A, PTPN1, MAP3K14, ERC1, IKBKB, DUSP7
GO:0006796 ∼ phosphate metabolic process 0.00122 STK38, SLC20A1, ERBB3, NUAK1, MKNK1, ABI1, PIP5K1A, TRIB1, MAP3K3, SRPK2, MINPP1, ADAM10, STK24, MSH2, PRKCI, PKN2, PTPN12, GAK, MAP4K4, MTMR11, MAPK6, GSK3B, DYRK1A, PTPN1, MAP3K14, ERC1, IKBKB, DUSP7
GO:0006468 ∼ protein amino acid phosphorylation 0.00498 SRPK2, ADAM10, STK38, STK24, NUAK1, ERBB3, PRKCI, PKN2, MKNK1, ABI1, TRIB1, GAK, MAP4K4, MAPK6, MAP3K3, GSK3B, DYRK1A, IKBKB, ERC1, MAP3K14
GO:0016310 ∼ phosphorylation 0.00801 SRPK2, ADAM10, STK38, ERBB3, MSH2, STK24, NUAK1, PRKCI, PKN2, MKNK1, ABI1, PIP5K1A, TRIB1, GAK, MAP4K4, MAPK6, MAP3K3, GSK3B, DYRK1A, IKBKB, ERC1, MAP3K14
GO:0008104 ∼ protein localization 0.01176 STON2, SEC23A, XPO1, AP1M1, NUP160, PRKCI, CENPF, TMSB10, TRAM2, TAP2, GSK3B, NUP210, TAP1, PIKFYVE, SNX21, RAB23, SCG5, SUPT7L, SAR1B, RAB10, ERC1, KPNA2, KPNB1
GO:0043407 ∼ negative regulation of MAP kinase activity 0.00991 STK38, PTPN1, SPRY4, DUSP7
GO:0042981 ∼ regulation of apoptosis 0.0165 DLC1, DPF2, IER3, ING3, SYVN1, ERBB3, MSH2, KLF10, PRKCI, AKAP13, CD70, PAWR, SOD2, TNFRSF10A, BAG4, TIAM1, GSK3B, GLO1, APBB2, IKBKB, MYC
GO:0043067 ∼ regulation of programmed cell death 0.0181 DLC1, DPF2, IER3, ING3, SYVN1, ERBB3, MSH2, KLF10, PRKCI, AKAP13, CD70, PAWR, SOD2, TNFRSF10A, BAG4, TIAM1, GSK3B, GLO1, APBB2, IKBKB, MYC
GO:0015031 ∼ protein transport 0.0188 STON2, SEC23A, XPO1, AP1M1, NUP160, PRKCI, CENPF, TRAM2, TAP2, GSK3B, NUP210, TAP1, SNX21, RAB23, SCG5, SAR1B, RAB10, ERC1, KPNA2, KPNB1
GO:0010941 ∼ regulation of cell death 0.0188 DLC1, DPF2, IER3, ING3, SYVN1, ERBB3, MSH2, KLF10, PRKCI, AKAP13, CD70, PAWR, SOD2, TNFRSF10A, BAG4, TIAM1, GSK3B, GLO1, APBB2, IKBKB, MYC
GO:0045184 ∼ establishment of protein localization 0.0204 STON2, SEC23A, XPO1, AP1M1, NUP160, PRKCI, CENPF, TRAM2, TAP2, GSK3B, NUP210, TAP1, SNX21, RAB23, SCG5, SAR1B, RAB10, ERC1, KPNA2, KPNB1
GO:0008219 ∼ cell death 0.0211 FUS, DPF2, DLC1, IER3, MICB, ERBB3, MSH2, AKAP13, RNF216, PAWR, ITPR1, SOD2, TNFRSF10A, BAG4, UNC5B, TIAM1, SIAH1, MYC, SPAST
GO:0010033 ∼ response to organic substance 0.0217 ADAM10, KAT2B, ERBB3, MSH2, KLF10, PRKCI, CALCOCO2, APPL1, TRIB1, B2M, HDAC4, PRKAR2A, SDC1, HDAC2, ADM, TAP2, CTSC, PTPN1, MYC
GO:0016265 ∼ death 0.0225 FUS, DPF2, DLC1, IER3, MICB, ERBB3, MSH2, AKAP13, RNF216, PAWR, ITPR1, SOD2, TNFRSF10A, BAG4, UNC5B, TIAM1, SIAH1, MYC, SPAST
GO:0044265 ∼ cellular macromolecule catabolic process 0.0228 ADAM10, SYVN1, USP1, RNH1, UBE2V2, RNF216, MYLIP, UBE2Q2, ZFP36L2, FBXW7, GMCL1, PSMD3, ZMPSTE24, SIAH1, PCYOX1, USP33, MYC, FBXO11, USP31
GO:0007049 ∼ cell cycle 0.0405 E2F3, KAT2B, MSH2, PAPD7, CENPF, APPL1, GAK, SASS6, MAPK6, GSK3B, PRDM5, PSMD3, ZNF318, HBP1, SIAH1, APBB2, KPNA2, MYC, SPAST
GO:0009057 ∼ macromolecule catabolic process 0.0427 ADAM10, SYVN1, USP1, RNH1, UBE2V2, RNF216, MYLIP, UBE2Q2, ZFP36L2, FBXW7, GMCL1, PSMD3, ZMPSTE24, SIAH1, PCYOX1, USP33, MYC, FBXO11, USP31
KEGG pathway hsa05210:Colorectal cancer 0.0377 MSH2, GSK3B, APPL1, MYC, FZD7
hsa04210:Apoptosis 0.0421 TNFRSF10A, PRKAR2A, EXOG, IKBKB, MAP3K14
hsa00562:Inositol phosphate metabolism 0.0477 MINPP1, TPI1, PIKFYVE, PIP5K1A
hsa05169:Epstein-Barr virus infection 0.00175 POLR3F, XPO1, HDAC4, GTF2E2, HDAC2, GSK3B, PSMD3, MAP3K14, IKBKB, MYC
hsa05166:HTLV-I infection 0.0122 WNT5A, XPO1, E2F3, KAT2B, MAP3K3, GSK3B, MAP3K14, IKBKB, MYC, FZD7
hsa05205:Proteoglycans in cancer 0.0267 WNT5A, EIF4B, SDC1, TIAM1, ERBB3, MYC, FZD7, ITPR1