Table 4. Independent prognostic factors for LSCC by multivariate Cox regression.
| OS | RFS | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | P-value | HR | 95% CI | ID | P-value | HR | 95% CI | ||
| Lower limit | Upper limit | Lower limit | Upper limit | ||||||
| TRAPPC10 | 0.0106 | 0.0941 | 0.01535 | 0.5768 | SLC44A1 | 0.0055 | 0.1719 | 0.0496 | 0.5958 |
| Alcohol | 0.0252 | 0.0391 | 0.00229 | 0.668 | THEM4 | 0.0101 | 0.2215 | 0.07023 | 0.6988 |
| SLC39A14 | 0.0289 | 9.37 | 1.26 | 69.8 | RRM2 | 0.0151 | 34.8562 | 1.99009 | 610.503 |
| SOD2 | 0.0456 | 2.748 | 1.01992 | 7.4038 | Age | 0.0875 | 0.06502 | 0.00283 | 1.494 |
| SCG5 | 0.0515 | 8.6 | 0.986 | 75.1 | T | 0.1882 | 0.09721 | 0.00302 | 3.129 |
| Grade | 0.0536 | 0.0053 | 0.000025 | 1.09 | Stage | 0.1883 | 14.2194 | 0.27247 | 742.056 |
| MICAL2 | 0.0872 | 0.141 | 0.0149 | 1.33 | ZFP1 | 0.2108 | 3.5709 | 0.48649 | 26.2105 |
| RUSC1-AS1 | 0.0894 | 1.1434 | 0.97957 | 1.3347 | LINC00324 | 0.2134 | 1.5429 | 0.77921 | 3.0549 |
| Gender | 0.1057 | 0.002 | 1.08E−06 | 3.72 | PCYOX1 | 0.2206 | 0.16586 | 0.009362 | 2.939 |
| CNPY3 | 0.1069 | 43.1 | 0.444 | 4170 | CELSR2 | 0.2233 | 0.12475 | 0.004376 | 3.556 |
| PUS1 | 0.1534 | 0.0927 | 0.00354 | 2.43 | NXPH4 | 0.2429 | 0.58688 | 0.239935 | 1.435 |
| HPN | 0.1538 | 0.398 | 0.112 | 1.41 | Gender | 0.2507 | 0.11327 | 0.002754 | 4.658 |
| hsa-mir-16-2 | 0.1626 | 0.5574 | 0.24539 | 1.266 | PTPN1 | 0.2567 | 17.1232 | 0.126445 | 2318.83 |
| Age | 0.1641 | 0.0323 | 0.000256 | 4.07 | AFF4 | 0.3093 | 17.52882 | 0.070156 | 4379.665 |
| PTPN12 | 0.204 | 42.7 | 0.13 | 14000 | PYGO2 | 0.3218 | 0.06118 | 0.000243 | 15.379 |
| ADAM10 | 0.245 | 0.136 | 0.00472 | 3.93 | SLC39A14 | 0.3303 | 1.5919 | 0.62436 | 4.0587 |
| LRRC40 | 0.2467 | 0.0333 | 0.000106 | 10.5 | SPRY4 | 0.3574 | 1.6716 | 0.55973 | 4.9922 |
| Stage | 0.2589 | 185 | 0.0215 | 158000 | Grade | 0.4953 | 0.24206 | 0.004104 | 14.277 |
| RAB10 | 0.2779 | 0.0066 | 7.71E-07 | 57.1 | MAP4K4 | 0.4973 | 0.21996 | 0.002775 | 17.436 |
| T | 0.2814 | 0.0214 | 0.000020 | 23.3 | hsa-mir-16-2 | 0.50105 | 0.7001 | 0.24778 | 1.978 |
| TSC22D2 | 0.3088 | 1.7322 | 0.60129 | 4.99 | ERBB3 | 0.6193 | 2.56113 | 0.06268 | 104.645 |
| FUS | 0.3262 | 0.0128 | 2.11E-06 | 77.1 | PTBP1 | 0.629 | 8.46884 | 0.00146 | 49149.03 |
| DLC1 | 0.3279 | 0.168 | 0.00472 | 5.99 | tobacco | 0.6901 | 0.59073 | 0.04442 | 7.856 |
| PRPSAP2 | 0.328 | 0.0598 | 0.000212 | 16.9 | SCG5 | 0.7040 | 1.2036 | 0.46263 | 3.1314 |
| TSEN15 | 0.3295 | 2.1853 | 0.45397 | 10.5197 | PRDM5 | 0.7108 | 1.45392 | 0.20106 | 10.514 |
| ST3GAL2 | 0.3643 | 1.4916 | 0.62882 | 3.5381 | N | 0.7903 | 0.69963 | 0.05030 | 9.731 |
| PYGO2 | 0.4608 | 6.86 | 0.0412 | 1140 | LRRC8E | 0.7914 | 0.70897 | 0.05545 | 9.065 |
| E2F3 | 0.4736 | 2.69 | 0.18 | 40.2 | MICAL2 | 0.8244 | 1.2676 | 0.15616 | 10.289 |
| N | 0.5037 | 0.203 | 0.00188 | 21.8 | SDC1 | 0.8476 | 1.1355 | 0.31079 | 4.1489 |
| SPRY4 | 0.5551 | 1.3026 | 0.54132 | 3.1346 | hsa-mir-7-2 | 0.8556 | 1.1305 | 0.30175 | 4.2351 |
| TAP2 | 0.574 | 0.7112 | 0.21679 | 2.3332 | hsa-mir-10a | 0.9186 | 0.9692 | 0.53189 | 1.7661 |
| NXPH4 | 0.6486 | 0.784 | 0.276 | 2.23 | ST3GAL2 | 0.9385 | 0.9482 | 0.24524 | 3.666 |
| TCFL5 | 0.6954 | 0.7436 | 0.16866 | 3.278 | Alcohol | 0.9937 | 1.01803 | 0.01187 | 87.316 |
| Tobacco | 0.717 | 1.67 | 0.105 | 26.5 | |||||
| SNX21 | 0.8253 | 0.8703 | 0.25359 | 2.9871 | |||||
| hsa-mir-10a | 0.8392 | 0.9451 | 0.54739 | 1.6316 | |||||
| PAWR | 0.842 | 1.7 | 0.00918 | 315 | |||||
| SAR1B | 0.9106 | 1.25 | 0.0244 | 64.3 | |||||
| ITPR1 | 0.9121 | 1.19 | 0.0539 | 26.3 | |||||
| AHCYL2 | 0.9767 | 1.06 | 0.0236 | 47.5 | |||||
Notes.
P-value < 0.05 shown in bold.