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. 2019 Aug;16(3):530–541. doi: 10.20892/j.issn.2095-3941.2018.0380

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Copyright 2019 Cancer Biology & Medicine

This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/

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CDKN1C and TP53INP1 are suppressed by H3K27me3 and restored by UNC1999 treatment in MCL cells. (A) Z138 and Mino cells were treated with UNC1999 for 48 h and determined with CDKN1C and TP53INP1 expression by qRT-PCR. (B, C) H3K27me3 abundance on the promoters of CDKN1C and TP53INP1 were determined by ChIP-qPCR in Z138 and Mino cells respectively with UNC1999 treatment for 48 h. Data are represented as the mean ± SD. All experiments were repeated at least three times. * P < 0.05 and ** P < 0.01.