1.

Demographics of 64 patients with pathogenic germline BRCA1/2 mutations

Chrematistics	No. of patients (%)
Gender
Male	38 (59.4%)
Female	26 (40.6%)
Age, years (median and range)	59 (33-77)
Smoking status
Yes	13
Non/ever	43
No information	8
Histology
Adenocarcinoma	55 (86%)
Squamous cell	2 (3%)
Large cell	2 (3%)
Not specified	5 (8%)
Pathogenic/likely pathogenic germline mutations detected
BRCA1	15 (23.4%)
BRCA2	49 (76.6%)
Treatment history
Treatment-naive	35 (54.7%)
Previously treated	29 (45.3%)