Table 2.
Univariate and Multivariate Analyses of Factors Associated with Eradication Success (7d-TT vs 10d-CT)
| Characteristics | Eradication | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|
|
|
|
|
|||||
| Total (n=760) | Yes (n=552) | No (n=208) | Unadjusted OR (95% CI) | p-value | Unadjusted OR (95% CI) | p-value | |
| Group | |||||||
| TT | 377 (100) | 241 (63.9) | 136 (36.1) | Reference | Reference | ||
| CT | 383 (100) | 311 (81.2) | 72 (18.8) | 2.43 (1.75–3.39) | <0.001 | 3.39 (2.33–4.94) | <0.001 |
| Age, yr | |||||||
| <60 | 480 | 361 (75.2) | 119 (24.8) | Reference | Reference | ||
| ≥60 | 280 | 191 (68.2) | 89 (31.8) | 0.70 (0.51–0.98) | 0.030 | 0.63 (0.44–0.90) | 0.012 |
| Sex | |||||||
| Male | 413 | 319 (77.2) | 94 (22.8) | Reference | 0.002 | Reference | |
| Female | 347 | 233 (67.1) | 114 (32.9) | 0.60 (0.43–0.83) | 0.56 (0.39–0.80) | 0.001 | |
| Compliance | |||||||
| <80 | 116 | 48 (41.4) | 68 (58.6) | Reference | Reference | ||
| ≥80 | 644 | 504 (78.3) | 140 (21.7) | 5.10 (3.37–7.71) | <0.001 | 7.22 (4.57–11.41) | <0.001 |
| General medical history* | - | ||||||
| No | 428 | 317 (74.1) | 111 (25.9) | Reference | |||
| Yes | 332 | 235 (70.8) | 97 (29.2) | 0.84 (0.61–1.16) | 0.310 | ||
| Medical history of GI diseases† | - | ||||||
| No | 196 | 138 (70.4) | 58 (29.6) | Reference | |||
| Yes | 564 | 414 (73.4) | 150 (26.6) | 1.16 (0.81–1.66) | 0.410 | ||
| Family history of gastric cancer | - | ||||||
| No | 651 | 471 (72.4) | 180 (27.6) | Reference | |||
| Yes | 109 | 81 (74.3) | 28 (25.7) | 1.10 (0.69–1.75) | 0.670 | ||
| Concomitant medication | - | ||||||
| No | 439 | 327 (74.5) | 112 (25.5) | Reference | |||
| Yes | 321 | 225 (70.1) | 96 (29.9) | 0.80 (0.58–1.10) | 0.180 | ||
Data are presented as number or number (%).
7d, 7 days; TT, triple therapy; CT, concomitant therapy; OR, odds ratio; CI, confidence interval; GI, gastrointestinal.
General medical history includes hypertension, arrhythmia, myocardial infarction, heart failure, diabetes mellitus, asthma, chronic obstructive pulmonary disease, liver cirrhosis, renal failure, and any cancer except GI cancer;
Past medical history of GI diseases includes esophagitis, gastric ulcer, duodenal ulcer, gastric cancer, past history of abdominal surgery, gastrectomy, intractable iron deficiency anemia, chronic idiopathic thrombocytopenic purpura, atrophic gastritis, and nonulcer dyspepsia.