Table 3.

Univariate and Multivariate Analyses of Factors Associated with Eradication Success

Characteristics	Eradication			Univariate analysis		Multivariate analysis
	Total (n=754)	Yes (n=529)	No (n=225)	Unadjusted OR (95% CI)	p-value	Unadjusted OR (95% CI)	p-value
Group
TT	377	241 (63.9)	136 (36.1)	Reference		Reference
ST	377	288 (76.4)	89 (23.6)	1.82 (1.32–2.50)	<0.001	2.10 (1.50–2.95)	<0.001
Age, yr
<60	476	341 (71.6)	135 (28.4)	Reference
≥60	278	188 (67.6)	90 (32.4)	0.82 (0.60–1.14)	0.246
Sex
Male	416	316 (75.9)	100 (24.1)	Reference		Reference
Female	338	213 (63.0)	125 (37.0)	0.53 (0.39–0.73)	<0.001	0.57 (0.41–0.80)	0.001
Compliance
<80	106	43 (40.6)	63 (59.4)	Reference		Reference
≥80	648	486 (75)	162 (25)	4.39 (2.86–6.73)	<0.001	4.79 (3.07–7.47)	<0.001
General medical history*
No	415	292 (70.4)	123 (29.6)	Reference
Yes	339	237 (70.0)	102 (30.0)	0.97 (0.71–1.33)	0.890
Medical history of GI diseases†
No	195	138 (70.7)	57 (29.2)	Reference
Yes	559	391 (70.0)	168 (30.0)	0.96 (0.67–1.37)	0.830
Family history of gastric cancer
No	651	456 (70.0)	195 (30.0)	Reference
Yes	103	73 (70.9)	30 (29.1)	1.04 (0.65–1.64)	0.860
Concomitant medication
No	420	303 (72.1)	117 (27.9)	Reference
Yes	334	226 (67.7)	108 (32.3)	0.80 (0.59–1.10)	0.180

Data are presented as number or number (%).

OR, odds ratio; CI, confidence interval; TT, triple therapy; ST, sequential therapy; GI, gastrointestinal.

^*General medical history includes hypertension, arrhythmia, myocardial infarction, heart failure, diabetes mellitus, asthma, chronic obstructive pulmonary disease, liver cirrhosis, renal failure, and any cancer except GI cancer;

^†Past medical history of GI diseases includes esophagitis, gastric ulcer, duodenal ulcer, gastric cancer, past history of abdominal surgery, gastrectomy, intractable iron deficiency anemia, chronic idiopathic thrombocytopenic purpura, atrophic gastritis, and nonulcer dyspepsia.