Table 2.
Proportion of Fully Fed Mosquitoes After Direct Skin Feeding and Membrane Feeding
| Feeding Method |
Human Subjects; Mosquitoes Fully Fed (%)a |
Risk Ratio (95% Confidence Interval), P Value | |||||||
|---|---|---|---|---|---|---|---|---|---|
| IVM-3x600 | IVM-3x300 | Placebo | IVM-3x600 vs Placebo | IVM-3x300 vs Placebo | IVM-3x600 vs IVM-3x300 | ||||
| Direct skin | 22; | 938/1096 (85.6) | 24; | 1015/1199 (84.7) | 23; | 988/1151 (85.8) | 1.00 (0.89–1.11), .95 | 0.99 (0.88–1.10), .80 | 1.01 (0.91–1.12), .84 |
| Membrane | 22; | 2584/3300 (78.3) | 24; | 2533/3613 (70.1) | 23; | 2263/3455 (65.5) | 1.20 (0.99–1.45), .07 | 1.07 (0.88–1.30), .51 | 1.12 (0.94–1.33), .20 |
Abbreviations: IVM-3x300, ivermectin 300 mcg/kg/day for 3 days; IVM-3x600, ivermectin 600 mcg/kg/day for 3 days.
aThe number of mosquitoes fully fed out of the number of mosquitoes offered a blood meal.