4.

管静脉曲张相关指标（指数）联合诊断评价

Performance of different combinations of the indexes in diagnosis of esophageal varices

Disease	Index	Cases (%)	Se (%)	NPV	NLR	Sp (%)	PPV	PLR
V: Esophageal varices; HREV: High risk esophageal varices; Se: Sensitivity; Sp: Specificity; PPV: Positive predictive value; NPV: Negative predictive value; PLR: Positive likelihood ratio; NLR: Negative likelihood ratio; PSR: Platelet/ splenic thickness ratio; SPT: Splenic thickness; US: Ultrasound score; PLT: Platelet; SVD: Splenic vein diameter; USWA: US-SPT-WBC-ALB (prediction model for EV); EVS: Esophageal varices score; SPA: SPT-ALB (prediction model for HREV). →: Stepwise combination; +: Synchronous combination.
EV
	SPT≥54→US≥10	125 (61.9)	72.1	37.0	0.34	81.8	95.2	4.0
	SPT≥54→PLT≤50	87 (43.1)	51.2	28.7	0.50	97.1	98.9	17.7
	SPT≥54→SVD≥10	86 (42.6)	50	27.6	0.55	94.1	97.7	8.5
	SPT≥54→EVS≥3	74 (36.6)	44.0	26.6	0.56	100	100	∝
	SPT≥54→PSR < 0.75	75 (37.1)	44.6	26.8	0.55	100	100	∝
	SPT≥54→USWA≥3.34	93 (46.0)	54.2	30.6	0.46	100	100	∝
	SPT < 37+PSR > 3.646	12 (7.4)	100	100	0	35.3	88.4	1.5
	SPT < 37+USWA < -0.30	17 (8.4)	100	100	0	50	90.8	2
HREV
	SPT < 37+SPA < -0.68	13 (6.4)	100	100	0	15.5	62.4	1.2
	SPA≥2.52→SPT≥78	11 (5.4)	9.3	44.0	0.91	100	100	∝