3.

硼替佐米联用obatoclax在Jurkat细胞中的协同细胞毒性作用

Bortezomib combined with obatoclax show synergistic cytotoxicity in Jurkat cells. A: Bcl-2 inhibitors decrease the viability of Jurkat cells (n=3); B: Cytotoxicity of bortezomib in combination with obatoclax, AT-101, or ABT-199 determined by MTT assay (n=3); C: Cell apoptosis determined by phosphatidylserine (PS) externalization and binding of Annexin Ⅴ (n=3). *P < 0.05