Skip to main content
. 2019 Apr 20;39(4):401–408. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2019.04.04

5.

5

硼替佐米联用obatoclax在Jurkat细胞中诱导了未折叠蛋白反应

Bortezomib combined with obatoclax induces unfolded protein response (UPR) in Jurkat cells. A: Protein expressions of Bip, p-JNK, and p-p38 determined by Western blotting (n=3); B: mRNA levels of key regulators of the UPR determined by realtime PCR (*P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001 vs control); C: Protein expression of CHOP determined by Western blotting (n=3); D: Cell viability determined by MTT assay; E: Cellular apoptosis determined by PS externalization and binding of Annexin Ⅴ (n=3)