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. 2019 Apr 20;39(4):428–436. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2019.04.08

1.

ALS患者CSF中蛋白参与生物过程的种类

Functional classification of the proteins involved in the biological processes in CSF of patients with ALS

Classification CSF ofALS patients with medullary onset CSF ofALS patients with limb onset
Upregulated protein
(species)
Down-regulated protein (species) Upregulated protein
(species)
Down-regulated protein (species)
Physiological process 38 3 12 8
Single organ process 34 5 12 14
Multiple organ process 25 1 10 3
Metabolic process 20 3 5 11
Immune response 6 3 3 9
Stress response 22 6 8 11
Biological regulation 25 4 11 11
Signal transmission 17 1 5 3
Positioning function 14 1 6 3
Motion function 8 1 3 3
Bioadhesion process 10 0 4 2
Developmental process 21 0 9 5