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. 2019 Sep 9;5(2):e001035. doi: 10.1136/rmdopen-2019-001035

Table 3.

Grades of recommendation

Grade
A Consistent level 1 studies
B Consistent level 2 or 3 studies or extrapolations from level 1 studies
C Level 4 studies or extrapolations from level 2 or 3 studies
D Level 5 evidence or troublingly inconsistent or inconclusive studies of any level