1.
db/db小鼠一般情况及生化指标
Effect of irbesartan on heart weight, body weight and serum biochemical parameters in db/db mouse (Mean±SD)
| Group | n | HWT (mg) | BWT (g) | FBG (mmol/L) | TC (mmol/L) | TG (mmol/L) |
| HWT: Heart weight; BWT: Body weight; FBG: Fasting blood glucose; TC: Total cholesterol; TG: Triglyceride. *P < 0.05, **P < 0.01 vs db/+. | ||||||
| db/+ | 9 | 125.82±37.57 | 23.34±2.82 | 6.20±2.03 | 2.17±0.24 | 0.71±0.11 |
| db/db | 12 | 131.33±13.77 | 44.50±6.91** | 39.59±6.75** | 4.08±0.66** | 1.34±0.48* |
| db/db+ibesartan | 10 | 121.58±18.67 | 42.87±6.44** | 36.14±5.55** | 3.86±0.43** | 1.18±0.34* |