3.
上调基因功能和通路富集分析
Function and KEGG pathway analysis of the down-regulated genes
| Term | Description | Count | P |
| down-regulated | |||
| GO: 0051789 | Response to protein stimulus | 20 | 8.08E-09 |
| GO: 0006986 | Response to unfolded protein | 15 | 1.96E-07 |
| GO: 0001775 | Cell activation | 29 | 1.80E-06 |
| GO: 0046649 | Lymphocyte activation | 23 | 3.12E-06 |
| GO: 0010033 | Response to organic substance | 51 | 6.90E-06 |
| GO: 0042981 | Regulation of apoptosis | 55 | 7.44E-06 |
| GO: 0045321 | Leukocyte activation | 25 | 7.54E-06 |
| GO: 0043067 | Regulation of programmed cell death | 55 | 9.70E-06 |
| GO: 0010941 | Regulation of cell death | 55 | 1.09E-05 |
| GO: 0008284 | Positive regulation of cell proliferation | 34 | 1.79E-05 |
| KEGG: hsa04060 | Cytokine-cytokine receptor interaction | 28 | 1.79E-05 |
| KEGG: hsa04660 | T cell receptor signaling pathway | 16 | 5.25E-05 |
| KEGG: hsa04010 | MAPK signaling pathway | 26 | 1.81E-04 |
| KEGG: hsa04630 | Jak-STAT signaling pathway | 17 | 9.75E-04 |
| KEGG: hsa04062 | Chemokine signaling pathway | 18 | 0.002763 |
| KEGG: hsa04115 | p53 signaling pathway | 9 | 0.0085092 |
| KEGG: hsa05210 | Colorectal cancer | 10 | 0.0098568 |
| KEGG: hsa05220 | Chronic myeloid leukemia | 9 | 0.0150118 |
| KEGG: hsa05200 | Pathways in cancer | 23 | 0.0252524 |
| KEGG: hsa04012 | ErbB signaling pathway | 9 | 0.0335255 |