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. 2018 Mar 20;38(3):261–267. [Article in Chinese] doi: 10.3969/j.issn.1673-4254.2018.03.04

4.

模块信号通路分析

KEGG pathway analysis of top 3 modules

Modules GeneSet P FDR Nodes
Module 1 Chemokine signaling pathway 6.49E-17 8.88E-14 ADCY1, CCR1, PF4, CXCR2, GNG11, CXCR3, CXCL6, CCL5, CXCL10, CCR9, CCR7, CCR6, PPBP, CXCR5, CXCR4, CCR4
Cytokine-cytokine receptor interaction 9.71E-12 7.79E-09 CCR1, PF4, CXCR2, CXCR3, CXCL6, CCL5, CXCL10, CCR9, CCR7, CCR6, CXCR5, PPBP, CXCR4, CCR4
Module 2 Ubiquitin mediated proteolysis 3.73E-12 3.62E-09 UBE2E3, CBLB, SOCS3, SOCS1, RBX1, CDC20, UBE2C, SMURF2, NEDD4L, FBXO2, UBA3, KEAP1
Module 3 Cell cycle 4.09E-06 0.003418 CCNB1, CDK1, CCNB2, PLK1, PCNA, BUB1B, CHEK1