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. 2018 Dec 20;38(12):1409–1414. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2018.12.02

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敲减Fascin抑制CaSki细胞裸鼠移植瘤生长

Fascin knockdown in CaSki cells inhibited xenograft tumor growth in nude mice (Mean±SD)

Group	Tumor volume (cm³)					Tumor weight (g)
Group	7d	12d	17d	22 d	27 d	Tumor weight (g)
^& P < 0.05 vs normal control; ^#P > 0.05 vs normal control.
Normal control	0.42±0.04	0.86±0.08	1.42±0.13	2.13±0.25	2.48±0.34	2.32±0.21
Negative control	0.40±0.06^#	0.89±0.12^#	1.38±0.11^#	2.16±0.27^#	2.51±0.30^#	2.39±0.41^#
Fascin miRNA	0.16±0.03 ^&	0.34±0.04 ^&	0.52±0.05 ^&	0.73±0.09 ^&	1.13±0.14 ^&	1.19±0.17 ^&
F	30.885	38.424	73.867	41.873	24.830	16.934
P	0.001	0.000	0.000	0.000	0.001	0.003