Fig. 4. Red cell susceptibility to osmotic lysis as function of genotype.

A. Osmotic lysis curves of red cells from WT mice (black triangles; pooled data from WT^SAD (n=3) and WT^Kcnn4 (n=4)) compared with osmotic lysis curves of red cells from Kcc1^−/−;Kcc3^−/− mice (open squares) and from Kcnn4^−/−;Kcc1^−/−;Kcc3^−/− mice (black circles). B. Osmotic lysis curves SAD mice (black squares) compared with those of red cells from SAD;Kcnn4^−/− mice (open circles), SAD;Kcc1^−/−;Kcc3^−/− mice (open triangles), and SAD;Kcnn4^−/−;Kcc1^−/−;Kcc3^−/− mice (black diamonds). Values are means ± SEM for (n) independently tested pooled samples from each genotype.