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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Blood Cells Mol Dis. 2019 Jul 17;79:102346. doi: 10.1016/j.bcmd.2019.102346

Fig. 6. Basal and stimulated K-Cl cotransport activity in SAD;Kcnn4−/− red cells compared with (A) SAD red cells and with (B) Kcnn4−/− red cells.

Fig. 6.

K-Cl cotransport activity was measured in isotonic medium (ISO), hypotonic medium (Hypo), isotonic medium containing 1 μM staurosporine (Stauro), and isotonic medium with added 500 mM urea (Urea). Values are means ± SEM for (n) independent experiments with blood pooled from 2–4 mice of indicated genotype. WT and SAD samples were compared for each condition by Mann-Whitney non-paired test. SAD mouse data in panel A is replicated from that of Figure 5.