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The various architectural patterns and cell shapes evaluated in this study are illustrated using IDH1 mutant intrahepatic cholangiocarcinomas. A) Simple tubular pattern; B) Anastomosing pattern; C) Compact tubular pattern; D) Solid pattern; E) Low cuboidal shape; F-G) Plump cuboidal shapes line lumens and polygonal cells are seen in crowded or solid areas; H) Clear cell features; I) Geographic fibrosis.
